Disease-Causing Nibbling Amoeba Hides by Displaying Proteins From Host Cells

This image shows amoebae (green) attacking human cells and displaying human proteins (red) on their surface. (Image credit: Hannah Miller)
Entamoeba histolytica kills human cells through trogocytosis or “cell nibbling” where amoebae bite off and ingest fragments of human cells. UC Davis researchers Katherine Ralston, Hannah Miller and Rene Suleiman discovered that the amoebae use this process to acquire and display human cell membrane proteins on their own surface. This protects them from immune responses. This image shows amoebae (green) attacking human cells and displaying human proteins (red) on their surface. (Image credit: Hannah Miller)

Research progress from the laboratory of Professor Katherine Ralston. [Article]